A 48-year-old woman has been diagnosed with extrahepatic cholestasis following a thorough history, ultrasound, and blood work. Which of the following symptoms most likely caused her to seek medical treatment, and what consequence to her health problem would the medical team anticipate?
A) Complaints of lower flank pain with consequences of impaired fat metabolism
B) Anorexia with consequences of impaired drug metabolism and blood filtration
C) Skin xanthomas (focal accumulations of cholesterol) with consequences of increased risk of bleeding due to deficient clotting factors
D) Pruritus with consequences of deficient levels of fat-soluble vitamins

Question

Quizplus · Accepted Answer

Pruritus is the most common symptom of cholestasis, and deficiencies in fat-soluble vitamins such as A, D, and K are frequent. Flank pain is not a noted complaint, and bile does not contribute to drug metabolism, blood filtration, or clotting factor production.

A 48-Year-Old Woman Has Been Diagnosed with Extrahepatic Cholestasis Following