A 51-year-old woman has been experiencing signs and symptoms of perimenopause and has sought help from her family physician. A deficiency in estrogen levels has been determined to be a contributing factor. Which of the following phenomena could potentially underlie the woman's health problem?
A) Sufficient synthesis of estrogen but inadequate vesicle-mediated release
B) Inadequate synthesis in the rough endoplasmic reticulum of her ovarian cells
C) Insufficient estrogen production within the smooth endoplasmic reticulum of the relevant cells
D) A lack of prohormone precursors needed for estrogen synthesis and release
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