HIV has an affinity for cells that bear the _______ antigen(s)on their surface.
A)CD4
B)HLA-B27
C)CD8
D)two of the above

Question

Quizplus · Accepted Answer

HIV has a specific affinity for cells that bear the CD4 antigen on their surface. CD4 is a glycoprotein found on the surface of immune cells such as T-helper cells, monocytes, macrophages, and dendritic cells. The virus uses CD4 as a receptor to bind to and enter the cells, which ultimately leads to a depletion of CD4 cells in the body and the development of AIDS. HLA-B27 and CD8 antigens are not specifically targeted by HIV.

HIV Has an Affinity for Cells That Bear the _______