Several drugs are used because they interfere with blood clotting. Which of the following agents used is inactivated by vitamin K?

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Quizplus · Accepted Answer

Warfarin (marketed in the United States as Coumadin) works by inactivating vitamin K-dependent coagulation factors. Excessive anticoagulation with warfarin can be reversed with the administration of vitamin K. (It is easy to remember that vitamin K is the vitamin used to restore coagulation to normal. Koagulation is the German word for coagulation and the word for which the vitamin was named.) Acetylsalicylic acid (aspirin) is a drug that irreversibly inactivates platelet aggregation. Clopidogrel also inhibits platelet aggregation by a mechanism that complements the action of aspirin. Heparins are anticoagulants that act by preventing the conversion of prothrombin to thrombin in the coagulation cascade

Several Drugs Are Used Because They Interfere with Blood Clotting