A flat area of skin that differs from the surrounding skin by being darker or lighter than it is called a:

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A macule is a flat spot on the skin that is darker or lighter than the surrounding skin. A papule is a raised area of skin (a bump or pimple) smaller than a peppercorn. A vesicle is a small blister (it contains fluid). A wart is a solid, irregular skin growth, with a rough, cauliflower-like surface, typically caused by a virus.

A Flat Area of Skin That Differs from the Surrounding