Anecdotal reports suggest that 3,4 methylenedioxymethamphetamine (MDMA) users report substantially more negative or depressed mood states in the days immediately following MDMA administration.

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MDMA, commonly known as ecstasy, is known to cause a significant depletion of serotonin in the brain following its use. This depletion can lead to negative mood states, including feelings of depression, in the days following MDMA administration, as reported by users and supported by scientific research.

Anecdotal Reports Suggest That 3,4 Methylenedioxymethamphetamine (MDMA) Users Report Substantially