The initial rate of distribution of a drug is heavily dependent on the ________ to various organs.

Question

Quizplus · Accepted Answer

A) The initial rate of distribution of a drug is heavily dependent on the blood flow to various organs. Lipid-soluble drugs enter the CNS rapidly. Because of the blood-brain barrier, certain drugs are poorly distributed to the CNS because they pass through the barrier. The three major influencing factors related to drug distribution are: blood flow to the body tissues, how drugs are able to exit the vascular system, and how drugs are able to enter body cells.

The Initial Rate of Distribution of a Drug Is Heavily