In a coupled reaction of a metabolic pathway, a spontaneous reaction provides the energy needed by a nonspontaneous one.

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In metabolic pathways, the energy released by spontaneous reactions (exergonic reactions) is often used to drive nonspontaneous reactions (endergonic reactions), making the overall process energetically favorable. This coupling of reactions is fundamental in biological systems to synthesize complex molecules and perform cellular work.

In a Coupled Reaction of a Metabolic Pathway, a Spontaneous