Globular Proteins in Water Typically Assume Their Specific Shapes Because $\alpha$

Globular proteins in water typically assume their specific shapes because

A) they are water-soluble due to the polar points located along the length of the protein molecules.
B) the nonpolar portion of the molecule is inside and the polar portion is outside, as stated by the folding rule.
C) they can assume the $\alpha$ -sheet form, which stretches along the surface of the solution.
D) all of the polar side chains in the molecular structure fold inward to be protected from the effects of the polarity of water.