A patient who is receiving a factor VIII concentrate to treat hemophilia A develops hives, a low-grade temperature elevation, and a stuffy nose. The nurse will prepare to:

Question

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Factor VIII concentrates can cause allergic reactions, which can range from mild to severe. This patient is showing signs of a mild reaction and can be managed with an antihistamine such as diphenhydramine. Epinephrine is used if there are signs of anaphylaxis, such as wheezing and shortness of breath. Antipyretics are not indicated for low-grade fevers. Respiratory support may be necessary with severe anaphylaxis.

A Patient Who Is Receiving a Factor VIII Concentrate to Treat