Which of the following details the correct sequence of events for RNA interference mediated by siRNA?
A) degradation of passenger RNA strand, binding of mRNA, formation of double-stranded RNA, cleavage by dicer, binding to RISC, cleavage of mRNA
B) binding to RISC, binding of mRNA, formation of double-stranded RNA, degradation of passenger RNA strand, cleavage by dicer, cleavage of mRNA
C) formation of double-stranded RNA, cleavage by dicer, binding to RISC, degradation of passenger RNA strand, binding of mRNA, cleavage of mRNA
D) binding of mRNA, formation of double-stranded RNA, degradation of passenger RNA strand, cleavage by dicer, binding to RISC, cleavage of mRNA
E) binding of mRNA, formation of double-stranded RNA, cleavage by dicer, degradation of passenger RNA strand, binding to RISC, cleavage of mRNA,
Correct Answer:
Verified
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