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Phosphoglucomutase Catalyzes the Reaction in Which a Phosphate Group Is \rightleftarrows

Question 39

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Phosphoglucomutase catalyzes the reaction in which a phosphate group is transferred from the C-1 of glucose to the C-6 of glucose (G1P \rightleftarrows G6P). A student incubates a 0.2 M solution of glucose-1-phosphate overnight with a small amount of the enzyme. At equilibrium the concentration of glucose-1-phosphate is 9.0 × 10-3 M and the concentration of glucose-6-phosphate is 19.1 × 10-2 M.
Calculate the equilibrium constant (Keq) and the standard state free energy ( Δ\Delta G°') for this reaction at 25°C.

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The equilibrium constant K

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