Chymotrypsin has a large specificity pocket to bind the aromatic amino acids while elastase has a very small specificity pocket meant to bind Ala or Gly. Which of the following amino acid substitutions changes the specificity pocket of chymotrypsin to that of elastase?
A) Trp Ser
B) Leu Ala
C) Gly Val
D) Lys Asp
E) Val Asn
Correct Answer:
Verified
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