Which of the following correctly describes the sequence of events in the kinesin reaction cycle? For simplicity, the two heads are referred to as head 1 and head 2. Head 1 starts as the leading head.
A) head 1 releases tubulin, ATP binds to head 1, head 2 swings forward, head 2 binds to tubulin, ADP release from head 2, ATP hydrolysis in head 1
B) ATP binds to head 1, head 2 swings forward, ADP release from head 2, ATP hydrolysis in head 1, head 2 binds to tubulin, head 1 releases tubulin
C) ATP binds to head 1, head 2 swings forward, head 2 binds to tubulin, ATP hydrolysis in head 1, ADP release from head 2, head 1 releases tubulin
D) ATP binds to head 1, head 2 swings forward, head 2 binds to tubulin, ADP release from head 2, ATP hydrolysis in head 1, head 1 releases tubulin
E) none of the above
Correct Answer:
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