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The Key Step in the Generation of "Safe" (Replication-Incompetent) Viral

Question 28

Multiple Choice

The key step in the generation of "safe" (replication-incompetent) viral particles for gene therapy is


A) creation of site-specific mutations in viral genes
B) provision of viral genes on a The key step in the generation of  safe  (replication-incompetent)  viral particles for gene therapy is A)  creation of site-specific mutations in viral genes B)  provision of viral genes on a  <sup>-</sup> (psi<sup>-</sup>)  DNA C)  use of a packaging cell line that is not immortalized D)  deletion of the viral reverse transcriptase gene- (psi-) DNA
C) use of a packaging cell line that is not immortalized
D) deletion of the viral reverse transcriptase gene

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