You have cloned the cDNA for human XPA. You now attempt to use the human XPA cDNA (linked to a promoter) to correct the genetic defect in mice that have the mouse equivalent of the human disease xeroderma pigmentosum, by making transgenic mice. Briefly explain how you would analyze the transgenic mice for:
Stable integration of the transgene into the mouse's genomic DNA
Transcription of the transgene
Translation of the transgene
Ability of the XPA protein to correct the genetic defect in the transgenic mice.

Question

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The Answer of You have cloned the cDNA for human XPA. You now attempt to use the human XPA cDNA (linked to a promoter) to correct the genetic defect in mice that have the mouse equivalent of the human disease xeroderma pigmentosum, by making transgenic mice. Briefly explain how you would analyze the transgenic mice for:
Stable integration of the transgene into the mouse's genomic DNA
Transcription of the transgene
Translation of the transgene
Ability of the XPA protein to correct the genetic defect in the transgenic mice.

You Have Cloned the CDNA for Human XPA