Eukaryotic ribosomes misincorporate one amino acid for every 1,000-10,000, whereas the eukaryotic replication machinery misincorporates one nucleotide for every ~1x10⁷, a number which goes down to ~1x10⁹ following activity of the mismatch repair machinery. (a) Why can the cell tolerate a higher rate of error in translation than in replication? (b) Besides errors that occur in the ribosome, what is another potential source of error in protein synthesis?

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The Answer of Eukaryotic ribosomes misincorporate one amino acid for every 1,000-10,000, whereas the eukaryotic replication machinery misincorporates one nucleotide for every ~1x10⁷, a number which goes down to ~1x10⁹ following activity of the mismatch repair machinery. (a) Why can the cell tolerate a higher rate of error in translation than in replication? (b) Besides errors that occur in the ribosome, what is another potential source of error in protein synthesis?

Eukaryotic Ribosomes Misincorporate One Amino Acid for Every 1,000-10,000, Whereas