Failure of the ribosome to remove an exon-exon junction complex (EJC) leads to

Name: Failure of the ribosome to remove an exon-exon junction complex (EJC) leads to
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Question

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Nonsense-mediated mRNA decay (NMD) is a surveillance pathway that targets mRNAs containing premature termination codons for degradation. The presence of an exon-exon junction complex (EJC) downstream of a stop codon is a key signal for NMD, indicating that the stop codon is premature. Failure to remove the EJC thus leads to NMD.

Failure of the Ribosome to Remove an Exon-Exon Junction Complex