Imagine you're assaying the DNase I sensitivity of the promoter regions of the beta-globin and vitellogenin genes in chicken liver, instead of in chick embryo erythroblasts. In this case you expect to find that:

Question

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The vitellogenin promoter is expected to be more sensitive to DNase I treatment in chicken liver because vitellogenin is a liver-specific protein, indicating that its promoter is likely to be more open and accessible in liver cells for transcription. In contrast, the beta-globin gene is typically expressed in erythroblasts, not liver cells, making its promoter less accessible and less sensitive to DNase I in this context.

Imagine You're Assaying the DNase I Sensitivity of the Promoter