Which statement best describes the key difference between the "enhanceosome" and "hit and run" models for transcriptional activation?
A) The "enhanceosome" model requires the involvement of both promoter proximal elements and the core promoter, whereas the "hit and run" model only involves promoter proximal elements.
B) The "enhanceosome" model requires that a stable transcriptional activation complex assembles in an ordered fashion, whereas the "hit and run" model suggests that such complexes are formed stochastically.
C) The "enhanceosome" model requires synergy between multiple transcriptional (co) activators, whereas the "hit and run" model allows that each transcriptional regulatory protein may function independently.
D) The "enhanceosome" model only applies to genes that undergo developmental regulation, whereas the "hit and run" model only applies to genes that undergo dynamic regulation even in a terminally differentiated cell.
Correct Answer:
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