Steroid hormones, such as glucocorticoids, bind to receptors inside the cell. The hormone-receptor complex is transported into the nucleus, where it can directly affect gene expression. To get from the location where the receptor binds the hormone to its site of action:

Question

Quizplus · Accepted Answer

Steroid hormones like glucocorticoids enter cells and bind to their receptors in the cytoplasm. The resulting receptor-hormone complex then moves into the nucleus through nuclear pore complexes to regulate gene expression, without needing to dissociate, bind to a carrier for solubility, or be activated by a signaling cascade.

Steroid Hormones, Such as Glucocorticoids, Bind to Receptors Inside the Cell