The disease xeroderma pigmentosum (XP) is a rare autosomal recessive condition in humans. Individuals with this condition are extremely sensitive to UV light and nucleotide excision repair activity is reduced. When cell cultures from normal individuals and from XP patients are irradiated with various doses of UV light and cultured in radiolabeled thymidine…
A) cells from XP patients incorporate about the same amount of radiolabeled thymidine into their DNA as the cells from normal individuals.
B) cells from XP patients incorporate significantly less radiolabeled thymidine into their DNA.
C) cells from XP patients incorporate significantly more radiolabeled thymidine into their DNA.
D) neither cells from XP patients nor cells from normal individuals will incorporate radiolabeled thymindine into their DNA after UV irradiation.
Correct Answer:
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A) direct
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