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Proline Is a "Helix-Breaking" Residue Because

Question 24

Multiple Choice

Proline is a "helix-breaking" residue because


A) its R-group is too large to be accommodated in the alpha helix interior
B) its R-group is too hydrophobic to interact with water surrounding the alpha helix
C) its backbone nitrogen can only form hydrogen bonds in the context of a pleated beta sheet
D) cyclization prevents its backbone nitrogen from participating in hydrogen bonding that stabilizes the helix

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