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Consider a Linear DNA Molecule of 20 Complete Turns (Or

Question 20

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Consider a linear DNA molecule of 20 complete turns (or twists, T=20) with 10.5 base pairs (bp) per turn in solution. If the double helix is underwound by one full turn to the left and then the ends are sealed together, the result is a strained circle with 11.67 bp per turn, where L (linking number) =19 and T=19. If one negative supercoil is spontaneously introduced, the DNA circle will have the following characteristics:


A) L=19, T=20, 11.6 bp/turn
B) L=19, T=20, 10.5 bp/turn
C) L=20, T=20, 10.5 bp/turn
D) L=20, T=20, 11.6 bp/turn

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