A Premenopausal Woman Has ER-Positive Breast Cancer, and Her Prescriber

A premenopausal woman has ER-positive breast cancer, and her prescriber has ordered tamoxifen [Nolvadex]. She asks the nurse if anastrozole [Arimidex] would work better for her. What will the nurse tell her?

A) Anastrozole is more likely to cause hot flushes than tamoxifen.
B) Anastrozole is more likely to promote endometrial carcinoma.
C) Cancer recurrence is higher with anastrozole.
D) Until she is postmenopausal, anastrozole will not be effective.