The end point of coronary heart disease is a heart attack (myocardial infarction). How is it caused?

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The end point of coronary heart disease, a heart attack (myocardial infarction), is primarily caused by the blockage (occlusion) of a blood vessel due to a clot. This clot can either form and block the artery directly or form on the artery wall and then break off, circulating until it lodges in a smaller vessel, causing occlusion. Both mechanisms lead to reduced blood flow and oxygen supply to the heart muscle, resulting in a heart attack.

The End Point of Coronary Heart Disease Is a Heart