A Patients Rheumatoid Arthritis (RA) Has Failed to Respond Appreciably

A patients rheumatoid arthritis (RA) has failed to respond appreciably to first-line treatments and the primary care provider has added prednisone to the patients drug regimen. What principle will guide this aspect of the patients treatment?

A) The patient will need daily blood testing for the duration of treatment.
B) The patient must stop all other drugs 72 hours before starting prednisone.
C) The drug should be used at the highest dose the patient can tolerate.
D) The drug should be used for as short a time as possible.