In mammals, the hormone epinephrine activates an intracellular signalling pathway that leads to the breakdown of glycogen in the liver. The binding of epinephrine to a G-protein linked receptor on the surface of liver cells activates a succession of relay molecules including the adenyl cyclase, cAMP and protein kinase A, the final protein to be activated is the enzyme glycogen phosphorylase, which catalyses the breakdown of glycogen to glucose-1-phosphate. In this signalling pathway, an increase in the concentration of cAMP would lead to an increase in the concentration of
A) adenyl cyclase.
B) inactive protein kinase A.
C) active protein kinase A.
D) the G-protein.
E) glycogen phosphorylase.

Question

Quizplus · Accepted Answer

An increase in cAMP concentration activates protein kinase A, converting it from its inactive form to its active form.

In Mammals, the Hormone Epinephrine Activates an Intracellular Signalling Pathway