The Specificity of an Enzyme Is Due to

The specificity of an enzyme is due to

A) the unique amino acid structure of the binding surface at the active site.
B) the fixed shape of the amino acids at the active site.
C) the specific covalent bonding between the substrate and the amino acids at the active site.
D) the ability of amino acids distal from the active site to react with the substrate and correctly align the substrate.
E) All of these answers are correct.