Suppose a serum VDRL gave a positive result, and CSF showed 8 nucleated cells/mm³.What follow up test should be used in the laboratory diagnosis of neurosyphilis if the CSF VDRL tested positive, and what follow-up test should be used in the laboratory diagnosis of neurosyphilis if the CSF VDRL tested negative?

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The serum VDRL demonstrates exposure to T.pallidum, and the presence of greater than 4 nucleated cells/mm³ in CSF demonstrates a CNS infection.With both of these tests being positive, there is indication of neurosyphilis.To confirm this, a CSF VDRL can be performed.A positive CSF VDRL does not require confirmatory treponemal testing.A negative CSF VDRL requires follow up with a fluorescent treponemal antibody test.

Suppose a Serum VDRL Gave a Positive Result, and CSF