Laboratory diagnosis of this disease is based on a two-tiered approach, with initial screening by IFA or ELISA and confirmation by Western blot.It is important that testing evaluate for IgM and IgG in order to increase chances of detecting and identifying this disease.

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Laboratory serodiagnosis of Lyme disease is complicated by many factors.As a result, CDC, FDA, and other organizations have recommended a two-tiered approach to testing for Lyme disease.In addition, the pattern of antibody recognition changes during the course of the infection.

Laboratory Diagnosis of This Disease Is Based on a Two-Tiered