Which of the following statements is true regarding posttranslational modification of alkaline phosphatase (ALP) isoenzymes?
A) ALP isoforms result from the cleavage of terminal amino acids, creating variations in electrical charge and allowing separation by electrophoresis.
B) ALP isoforms result from the addition of carbohydrate side chains, which do not significantly modify electrical charge, making separation by electrophoresis difficult.
C) ALP isoforms result from dephosphorylation reactions that significantly alter the charge of the isoforms, allowing separation by electrophoresis.
D) ALP isoforms result from the addition of lipoprotein side chains, which do not significantly modify electrical charge, making separation by electrophoresis difficult.
Correct Answer:
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