An Important Preanalytical Variable Is Associated with the Use or Non-Use

An important preanalytical variable is associated with the use or non-use of anticoagulants.Which of the following statements related to use or non-use of anticoagulants are correct?
1) The measured total protein level is the same in serum and heparinized plasma.
2) Platelets release potassium during clotting.
3) The use of EDTA plasma will falsely decrease plasma calcium.
4) Heparinized plasma is preferred over serum for cardiac marker evaluation.

A) 1, 2, 3, 4
B) 1, 2, 3
C) 2, 3, 4
D) 1, 3, 4