Suppose a laboratory is interested in changing from a manual assay for a given analyte to an automated assay for the analyte.Data collected by each of the two methods are unrelated, and the number of observations differs for each dataset.Which statistical method should be selected to determine if a significant difference exists between the means of the two methods?

Question

Quizplus · Accepted Answer

The unpaired t-test is used when the difference between the means of two independent samples are being compared.In this question, one dataset is associated with the manual assay, and one dataset is associated with the automated assay.When using the unpaired t-test, the datasets may be unrelated to the extent that data for analysis are from different patients, and there may be a different number of observations in each dataset.

Suppose a Laboratory Is Interested in Changing from a Manual