A method that falls in the six Sigma region of the Medical Decision Chart indicates that the relationship between the performance of the method and quality control is such that:

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Medical Decision Charts allow the relationship between method performance and quality control to be categorized based on the method's bias and imprecision.If a method's inherent errors are small relative to the CLIA '88 established allowable error, relatively weak quality-control procedures will be sufficient to detect errors that might exceed the allowable error.The six Sigma region of the chart is associated with methods that show the least inherent error.Thus the complexity of the quality-control procedures required to maintain the method's error below the allowable error is low.Specifically for six Sigma methods, one to two quality-control measures per run are required, along with a single 1₃s rule.For comparison, fair methods require four to six quality-control measures per run with the use of multiple quality-control rules.

A Method That Falls in the Six Sigma Region of the Medical