A man who does not suffer from sickle-cell anemia but is a carrier of the sickle-cell trait is married to a woman who is also a carrier for the sickle-cell trait. If they have a child, there is a ____ probability of that child suffering from sickle-cell anemia.

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When both parents are carriers of the sickle-cell trait, there is a 25% chance that their child will inherit two copies of the sickle-cell gene (one from each parent) and thus suffer from sickle-cell anemia. This follows Mendelian inheritance patterns for a recessive trait.

A Man Who Does Not Suffer from Sickle-Cell Anemia but Is