Which of the following statements are true regarding the laboratory analysis of vitamin status?
1)Measurement of urinary metabolites of a vitamin is one approach utilized for determining vitamin status.
2)Measurement of a biochemical function requiring the vitamin, with and without in-vitro addition of the cofactor form, is one approach utilized for determining vitamin status.
3)Detection of reduced serum concentrations of a vitamin is utilized to indicate a deficiency that interrupts cellular function.
4)Detection of vitamin values within a reference interval defined by population studies is utilized to indicate an adequate supply of that vitamin.

Question

Quizplus · Accepted Answer

Laboratory evaluation of human vitamin status has been approached in several ways,
including measurement of urinary metabolites of the vitamin and measurement of a biochemical function requiring the vitamin (such as enzymatic activity), with and without in-vitro addition of the cofactor form.Measurement of enzyme activity is a common function evaluated for this purpose.Reduced serum concentrations of a vitamin do not always indicate a deficiency that interrupts cellular function, just as values within a reference interval defined by population studies do not always reflect adequate supply.

Which of the Following Statements Are True Regarding the Laboratory