Which of the following occurs in Alzheimer's disease?

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In the early stages of Alzheimer's disease, there is a large decrease in choline acetyltransferase activity, along with degeneration of neurons using acetylcholine.In Huntington's disease, there is a degeneration of cholinergic neurons in the basal ganglia.Dysfunction of GABA-ergic systems is postulated in idiopathic generalized epilepsy, Huntington's disease, and anxiety disorders.Clinical disease states attributable to dopaminergic neuron dysfunction vary according to the anatomic location of the dysfunctional neurons.

Which of the Following Occurs in Alzheimer's Disease