Which amino acid residue of thyroglobulin is responsible for binding iodine in the formation of thyroid hormones?

Question

Quizplus · Accepted Answer

Intracellular thyroglobulin serves as a preformed matrix containing 123 tyrosine residues to which reactive iodine is attached to form monoiodotyrosine (MIT) and diiodotyrosine (DIT).Most iodination occurs when thyroglobulin is within the exocytic vesicles of the follicular cells.After their formation, enzymatic coupling of MIT and DIT takes place to form intrathyroglobulin T₃ and T₄.

Which Amino Acid Residue of Thyroglobulin Is Responsible for Binding