A 56-year-old man has been taking atorvastatin because of a poor lipid profile and a family history of cardiovascular disease. The statin family of drugs enhances endocytosis of low-density lipoprotein (LDL) from the blood. Endocytosis of LDL differs from phagocytosis of bacterial cells in which of the following ways?
A) Use of membrane-enclosed vesicles in the uptake process
B) Coupling with the lysosomal system
C) Dependence on acidification
D) Use of clathrin-coated pits
E) Use of hydrolases
Correct Answer:
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