Research scientists at a small biotech firm are investigating new methods of controlling the growth and metastasis of malignant cells in patients diagnosed with breast cancer. They have developed a novel peptide-based drug, potentially deliverable therapeutically, that disrupts the tumor cells' ability to adhere to the ECM, which in turn triggers apoptosis. Which of the following is a most likely target of such drugs?

Question

Quizplus · Accepted Answer

Integrins are proteins that mediate the attachment between a cell and the extracellular matrix (ECM). Disrupting integrin function can prevent tumor cells from adhering to the ECM, leading to apoptosis.

Research Scientists at a Small Biotech Firm Are Investigating New