A 12-year-old girl of African descent presents with anemia and a large percentage of her peripheral erythrocytes appear sickle-shaped. Genetic testing reveals homozygosity for sickle cell disease. In which of the following sites will the abnormal RBCs be removed from the circulation?
A) Thymic cortex
B) Periarteriolar lymphoid sheathes of splenic white pulp
C) Medullary sinuses of lymph nodes
D) Thymic medulla
E) Splenic cords (of Billroth)
Correct Answer:
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