A young child presents with hepatomegaly and renomegaly, failure to thrive, stunted growth, and hypoglycemia. A deficiency in glucose-6-phosphatase is identified and the diagnosis of von Gierke disease is made. What cellular structures would be expected to accumulate in hepatocytes during progression of this disorder?

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In von Gierke disease, there is a deficiency in glucose-6-phosphatase, leading to an inability to convert glycogen to glucose. This results in the accumulation of glycogen granules in hepatocytes.

A Young Child Presents with Hepatomegaly and Renomegaly, Failure to Thrive