In skeletal muscle, which of the following events occurs before depolarization of the T tubules in the mechanism of excitationcontraction coupling?

Question

Quizplus · Accepted Answer

[VI A 3]. In the mechanism of excitation-contraction coupling, excitation always precedes contraction. Excitation refers to the electrical activation of the muscle cell, which begins with an action potential (depolarization) in the sarcolemmal membrane that spreads to the T tubules. Depolarization of the T tubules then leads to the release of $\mathrm{Ca}^{2+}$ from the nearby sarcoplasmic reticulum (SR), followed by an increase in intracellular $\mathrm{Ca}^{2+}$ concentration, binding of $\mathrm{Ca}^{2+}$ to troponin $\mathrm{C}$, and then contraction.

In Skeletal Muscle, Which of the Following Events Occurs Before Ca2+\mathrm{Ca}^{2+}Ca2+

In Skeletal Muscle, Which of the Following Events Occurs Before $\mathrm{Ca}^{2+}$