Which of the following substances acts on its target cells via an inositol 1,4,5-triphosphate ( $\left.\mathrm{IP}_{3}\right)-\mathrm{Ca}^{2+}$ mechanism?

Question

Quizplus · Accepted Answer

[Chapter 7; Table 7.2]. Oxytocin causes contraction of the myoepithelial cells of the breast by an inositol 1,4,5-triphosphate ( $\left.\mathrm{IP}_{3}\right)-\mathrm{Ca}^{2+}$ mechanism. Somatomedins (insulin-like growth factor [IGF]), like insulin, act on target cells by activating tyrosine kinase. Antidiuretic hormone (ADH) acts on the $\mathrm{V}_{2}$ receptors of the renal collecting duct by a cyclic adenosine monophosphate (cAMP) mechanism (although in vascular smooth muscle it acts on $\mathrm{V}_{1}$ receptors by an $\mathrm{IP}_{3}$ mechanism).
Adrenocorticotropic hormone (ACTH) also acts via a cAMP mechanism. Thyroid hormone induces the synthesis of new protein (e.g., $\mathrm{Na}^{+}, \mathrm{K}^{+}$-adenosine triphosphatase [ATPase]) by a steroid hormone mechanism.

Which of the Following Substances Acts on Its Target Cells IP3)−Ca2+\left.\mathrm{IP}_{3}\right)-\mathrm{Ca}^{2+}IP3​)−Ca2+

Which of the Following Substances Acts on Its Target Cells $\left.\mathrm{IP}_{3}\right)-\mathrm{Ca}^{2+}$