The epineurium surrounds all of the fasciculi, their associated supporting connective tissue including blood vessels and lymphatics, and the perineuria.

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The epineurium is the outermost layer of connective tissue surrounding a peripheral nerve, encompassing all the nerve fascicles (bundles of nerve fibers), their supporting connective tissues, blood vessels, and lymphatics, as well as the perineurium (the sheath surrounding individual fascicles).

The Epineurium Surrounds All of the Fasciculi, Their Associated Supporting