Ms. Coidiuf, age 42, sustained a back injury three years ago, which responded well to treatment with nonsteroidal anti-inflammatory medication. Over the last six months, Ms. Coidiuf has been seeing her physician again with complaints of painful sensations "shooting" down her right hip. Despite careful attention, it appears that Ms. Coidiuf's pain is no longer responding to anti-inflammatory medication. Her physician prescribes a narcotic analgesic (moderate effectiveness) with acetaminophen, hoping this treatment might provide relief. Following three physical therapy sessions, the patient continues to report that she is "still miserable," leading her physician to believe that her condition is worsening. Heat packs, massage, and relaxation therapy have not been successful.
-What was the most likely target of pharmacological intervention for Ms. Coidiuf three years ago?
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