The pharmacist is preparing a presentation about antiseizure medications. The pharmacist plans to include the general mechanisms of actions for these medications. Which items would be appropriate to include? (Select all that apply.) Note: Credit will be given only if all correct choices and no incorrect choices are selected.

Question

Quizplus · Accepted Answer

Antiseizure medications work primarily by stabilizing neuronal membranes and reducing excitatory neurotransmitter activity. This is achieved by delaying the influx of sodium ions (A) and calcium ions (D), which are critical for action potential generation and propagation in neurons. Additionally, some antiseizure medications enhance the inhibitory effects of GABA by stimulating an influx of chloride ions (B), further dampening neuronal excitability. Increasing neuronal firing (C) would likely exacerbate seizures, not prevent them, and increasing an influx of potassium ions (E) is not a general mechanism of action for antiseizure medications.

The Pharmacist Is Preparing a Presentation About Antiseizure Medications