Which of the Following Best Supports the Distinctions Drawn Between

Which of the following best supports the distinctions drawn between the eastern and western hemispheres?

A) Until the fifteenth century C.E., no peoples from Afroeurasia had traveled to North or South America.
B) Until the fifteenth century C.E., no regular interactions existed between the peoples of Afroeurasia and North and South America.
C) The eastern and western hemispheres are naturally divided from one another.
D) The flora and fauna of the eastern and western hemispheres are entirely distinct from one another.