The R_fvalues determined on silica gel TLC plates for Compounds A, B, and C are tabulated in Table 11.5.
(a) In order to purify Compound A, which of the solvent systems should be used to develop the column in a flash chromatography procedure?
(b) Could 90 mg of a mixture of Compound A and Compound B be separated by macroscale flash column chromatography using 20% ethyl acetate-80% hexanes as the eluting sol- vent?
(c) Could 90 mg of a mixture of Compound A and Compound C be separated by macroscale flash column chromatography using 20% ethyl acetate-80% hexanes as the eluting sol- vent?

Question

Quizplus · Accepted Answer

The Answer of The R_fvalues determined on silica gel TLC plates for Compounds A, B, and C are tabulated in Table 11.5. (a) In order to purify Compound A, which of the solvent systems should be used to develop the column in a flash chromatography procedure? (b) Could 90 mg of a mixture of Compound A and Compound B be separated by macroscale flash column chromatography using 20% ethyl acetate-80% hexanes as the eluting sol- vent? (c) Could 90 mg of a mixture of Compound A and Compound C be separated by macroscale flash column chromatography using 20% ethyl acetate-80% hexanes as the eluting sol- vent?

The Rf values Determined on Silica Gel TLC Plates for Compounds

The R_fvalues Determined on Silica Gel TLC Plates for Compounds